I have a 300 shot of NOs direct port nitrous kit in the garage, I may pop it on the car one day, but just for show. Ron used to use NOS, although 600hp on NOS, kept blowing engines, Tony used to use NOS they kept blowing engines too. I guess if you do a 50shot of NOS and have gauges to monitor fuel pressure then you should be okay. The thing is, if the NOS fires, but extra fuel doesn't go in, then it doesn't take long before you engine start to melt, running very lean.
Although the alternative power adder would be turbo or supercharger they can be a bit costly, but if you engine goes then that could also be costly. I'm sure many NOS users may be able to tell you they got it reliable, but i haven't found a person yet. i think they started with sensible power, but got addicted, wanted more, and its gonna go bang.